Liver Wellness in the Media

Irish Independent - 15 January 2018

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4 days ago
About European Obesity Day - European Obesity Day

About European Obesity Day European Obesity Day 2018 will be held on Saturday 19 May. It brings together healthcare, patient and political communities who are keen to raise awareness of obesity and the many other diseases on which it impacts. The theme for EOD 2018 is Tackling Obesity Together. The....

1 week ago
Acute-on-chronic liver failure ICU outcomes similar to other patients

Patients with acute-on-chronic liver failure admitted to the ICU had clinical outcomes comparable to patients in the ICU without chronic liver disease and similar baseline severity of illness characteristics, according to a recently published study.“These findings suggest that ICU care in pati...

1 week ago
Could this vitamin A derivative cure liver cancer?

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2 weeks ago

'Alarming' New Numbers on Bacterial Infection in Cirrhosis
Neil Osterweil
April 12, 2018

Infections caused by multidrug-resistant bacteria, which are common in patients with cirrhosis, are associated with a significant elevation in risk for in-hospital mortality, results from a global study show. "The efficacy of first-line treatment is crucial to improve the survival of cirrhotic patients with bacterial infections," said Paolo Angeli, MD, PhD, from the University of Padova in Italy. For their study, Angeli and his colleagues followed 1302 patients with cirrhosis and bacterial or fungal infections until death, liver transplantation, or discharge. All were treated at one of 46 centers in North and South America, Europe, Africa, and Asia, and bacteria were considered multidrug-resistant if they were impervious to at least one agent in three or more antibiotic classes.

Angeli presented the results here at the International Liver Congress 2018.

In the study cohort, mean Model for End Stage Liver Disease (MELD) score was 21, 77% of the patients had ascites, and 35% had acute-on-chronic liver failure. Cirrhosis was caused by alcohol in 52% of patients, by hepatitis C virus in 20%, by hepatitis B virus in 8%, and by nonalcoholic steatohepatitis in 10%; the remaining 10% of patients had cirrhosis of unspecified origin. Of the infections, 48% were deemed to be community-acquired, 26% were nonhospital healthcare-associated, and 26% were nosocomial. The most common infections were spontaneous bacterial peritonitis (27%), urinary tract infections (22%), and pneumonia (19%). The most prevalent infectious organisms were Escherichia coli, Klebsiella pneumonia, Enterococcus, Staphylococcus aureus, and Pseudomnoas areuginosa.

Of the 959 micro-organisms isolated from the 740 patients with at least one positive culture, 58% were Gram-negative, 38% were Gram-positive, and 4% were fungi.

The global prevalence of multidrug-resistant bacteria was 34%, and the prevalence of ... See more

2 weeks ago

Difficult-to-Treat Sclerosing Cholangitis Eased With Statins.
Neil Osterweil

April 13, 2018

Statins can significantly reduce the risk for complications and death from primary sclerosing cholangitis, results from a Swedish registry study show. Primary sclerosing cholangitis is progressive, with no known therapy to prevent cirrhosis, liver transplant, or progression to cholangiocarcinoma, said Annika Bergquist, MD, PhD, from the Karolinska Institute in Stockholm.

However, recent evidence suggests that statins can be beneficial for patients with chronic and cholestatic liver disease, and might play a protective role in primary sclerosing cholangitis, she explained here at the International Liver Congress 2018. Bergquist and her colleagues drew on comprehensive birth-to-death Swedish registry data to explore the effects of different drugs, including statins, on the risk for death, liver transplantation, liver cancer, and variceal bleeding in patients with primary sclerosing cholangitis.

The team identified 2914 primary sclerosing cholangitis patients with data available on drug prescriptions, cancer status, general health, and death.

Drug exposure from the time of first prescription fulfillment was assessed on multivariate Cox regression analysis, with adjustments for age at diagnosis of primary sclerosing cholangitis, date of diagnosis, date of diagnosis of inflammatory bowel disease, and sex. The association with inflammatory bowel disease is strong. In Sweden, approximately 80% of primary sclerosing cholangitis patients have inflammatory bowel disease, Bergquist reported. In the study cohort, 58.3% of the patients also had a diagnosis of ulcerative colitis, 12.4% had a diagnosis of Crohn's disease, and 29.2% had mixed presentation of the two conditions.

The Swedish registry data were very high quality. Follow-up was nearly complete and the team was able to eliminate all patients with sclerosing cholangitis secondary to other conditions. However, they were ... See more

2 weeks ago

Poverty Harms Patients With Diabetes and Fatty Liver
Neil Osterweil

April 17, 2018
Medscape Medical News © 2018 WebMD, LLC

For patients with diabetes and nonalcoholic fatty liver disease (NAFLD), the risk for advanced hepatic fibrosis increases nearly three times when patients cannot consistently afford a healthy diet, results from a cross-sectional survey suggest. In fact, food insecurity — limited or uncertain availability of nutritionally adequate foods — is a better predictor of advanced fibrosis than other socioeconomic variables, said investigator Russell Rosenblatt, MD, from the New York Presbyterian Hospital in New York City.

"We recommend that hepatologists now think of screening these patients for food insecurity," he said here at the International Liver Congress 2018.

In the United States, food insecurity began to rise around 2008, coinciding with the Great Recession. It is estimated that nearly 50 million Americans are at risk of going hungry at least some of the time. In Europe, a similar trend began to emerge in 2010, with the advent of austerity measures, Rosenblatt reported. The link between food insecurity and diabetes, a major risk factor NAFLD, stems from the fact that calorie-dense but nutritionally poor foods tend to be considerably cheaper than healthy foods. People with food insecurity tend to have poor nutrition and higher levels of obesity, metabolic syndrome, and diabetes.

The American Diabetes Association has made screening for food insecurity when patients with diabetes are evaluated a class A recommendation.

To explore the strength of the association between food security and advanced fibrosis in patients with diabetes and NAFLD, Rosenblatt and his colleagues analyzed data on adults with diabetes from the 2005 to 2014 cycle of the National Health and Nutrition Examination Survey.

National Health and Nutrition Examination Survey
The team used a validated algorithm to identify patients with NAFLD and exclude people with ... See more

3 weeks ago
World Obesity Federation | €9.5m pan-European project to tackle adolescent obesity announced

€9.5m pan-European project to tackle adolescent obesity announced...

A consortium of 14 research and advocacy organisations meeting in Oslo, Norway, today (May 2nd) have launched a ground-breaking project involving young people themselves in a bid to tackle overweight and obesity. Supported by the European Commission, the budget of over €9.5m will provide a program...

3 weeks ago

Check out the “Non-Alcoholic Fatty Liver Disease (NAFLD) and Type 2 Diabetes” feature on TV3’s Sunday AM programme with Professor Suzanne Norris and her patient

3 weeks ago
Diabetes Ireland

Have you ever wanted to sit face to face with diabetes health care professionals outside of a hospital setting to learn more about your diabetes? Diabetes Ireland is delighted to offer you this opportunity. We have gathered professionals from a variety of fields in the area of Type 2 diabetes to answer YOUR questions.

To do this, join us in the Pillo Hotel, Ashbourne, Co Meath on 17Th May from 7-9pm

Follow the link below to register - Places are limited.

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